While most BCCs are detected and treated early, some can become advanced. Advanced BCC can penetrate deeply into the skin and nearby tissues (locally advanced) or spread to other parts of the body (metastatic). Advanced BCCs can cause significant tissue damage, affecting muscles, bones, and nerves.1
Unlike early-stage BCC, advanced BCC may not be completely removed with surgery alone. Therefore, treatment for advanced BCC may involve surgery, radiation, or systemic medications.1 Surgery is often recommended to remove cancer. If surgery is not an option, radiation therapy may be considered. If the cancer returns in nearby lymph nodes or other parts of the body, systemic treatments may be necessary.2
Early detection is crucial. Delaying a dermatologist visit can allow BCC to grow and become advanced. Regular skin checks and prompt treatment are essential to prevent complications. Advanced BCC can result from incomplete initial treatments, recurrent tumors, or neglect. Fear of diagnosis, treatment, or costs can lead to delays in seeking medical help, allowing the cancer to progress.1
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