People with all skin tones can develop cSCC, but those with lighter skin who spend lots of time in the sun, use or have used tanning beds, and take medications to prevent organ transplant rejection are at a higher risk.1
Not all cSCCs look the same. They can present as scaly red patches, open sores, rough, thickened or wart-like skin, or raised growths with a central depression. Basal cell carcinomas may appear as a flesh-colored, pearl-like bump, or a pinkish patch of skin. Melanoma often develops within an existing mole or suddenly emerges as a new dark spot on the skin.2
Basal Cell Carcinoma2
Squamous Cell Carcinoma2
Melanoma2
cSCC may develop from a precancerous growth called actinic keratoses, which manifest as dry, scaly patches or spots.2
Actinic keratoses2
The best way to prevent cSCC is by minimizing exposure to UV rays. When you’re outdoors, seek shade and use sun protection like clothing, sunglasses, and sunscreen. Avoid tanning beds, sun lamps, and harmful chemicals. Regularly check your skin for any new growths or abnormal areas, and steer clear of tobacco. Whenever feasible, avoid weakening your immune system.3
As a first step, your doctor will conduct a physical exam and inquire about your symptoms, medical history, and any unusual skin marks. The doctor will carefully observe the shape, size, color, and texture of any questionable spots. If the doctor suspects the spot to be cancerous, a portion of it will be removed and sent to a lab for analysis, which is known as a biopsy. If a lymph node appears abnormal, a lymph node biopsy may also be performed. Additionally, imaging tests like MRI or CT scans may be ordered if there is concern about the cancer spreading beyond the skin.4
Early-stage cSCCs can be successfully treated with local treatments such as surgery or radiation therapy, leading to a potential cure. Larger cSCCs and fast-growing cancers are more challenging to treat and have a higher risk of recurrence.5
No1
Squamous cell skin cancer usually grows slowly and is not life-threatening. However, in those with a compromised immune system, such as from organ transplant medications or leukemia, it can grow more aggressively. If untreated, it can penetrate deeply, damaging nerves, blood vessels, and spreading to other body parts, which can be deadly. Early detection is crucial for effective treatment, as it prevents deep growth and complications.1
